Evaluation of sample processing methods to improve the detection of Bacillus anthracis in difficult sample matrices.

ABSTRACT: Large area sampling approaches have been developed and implemented by the US Environmental Protection Agency (EPA) to increase sample sizes, and potentially representativeness, in outdoor urban environments (e.g., concrete, asphalt, grass/landscaping). These sampling approaches could be implemented in response to an outdoor biological contamination incident or bioterrorism attack to determine the extent of contamination and for clearance following remediation. However, sample collection over large areas often contains an extensive amount of co-collected debris and native background microorganisms that interfere with the detection of biological threat agents. Sample processing methods that utilize basic laboratory equipment amenable to field deployment were selected and applied to turbid aq

SUBMITTER: Nelson S 

PROVIDER: S-EPMC10410253 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature