Altered intrinsic brain activity and functional connectivity in COVID-19 hospitalized patients at 6-month follow-up.

ABSTRACT:

Background

Although most patients can recover from SARS-CoV-2 infection during the short-term, the long-term effects of COVID-19 on the brain remain explored. Functional MRI (fMRI) could potentially elucidate or otherwise contribute to the investigation of the long COVID syndrome. A lower fMRI response would be translated into decreased brain activity or delayed signal transferring reflecting decreased connectivity. This research aimed to investigate the long-term alterations in the local (regional) brain activity and remote (interregional) functional connection in recovered COVID-19.

Methods

Thirty-five previously hospitalized COVID-19 patients underwent 3D T₁weighed imaging and resting-state fMRI at 6-month follow-up, and 36 demographic-matched healthy controls

SUBMITTER: Li R 

PROVIDER: S-EPMC10410836 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature