Obstructive sleep apnea improves with non-invasive hypoglossal nerve stimulation using temporal interference.

ABSTRACT:

Background

Peripheral nerve stimulation is used in both clinical and fundamental research for therapy and exploration. At present, non-invasive peripheral nerve stimulation still lacks the penetration depth to reach deep nerve targets and the stimulation focality to offer selectivity. It is therefore rarely employed as the primary selected nerve stimulation method. We have previously demonstrated that a new stimulation technique, temporal interference stimulation, can overcome depth and focality issues.

Methods

Here, we implement a novel form of temporal interference, bilateral temporal interference stimulation, for bilateral hypoglossal nerve stimulation in rodents and humans. Pairs of electrodes are placed alongside both hypoglossal nerves to stimulate them synchronously a

SUBMITTER: Missey F 

PROVIDER: S-EPMC10410873 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature