Predictors of Failure of Noninvasive Ventilation in Critically Ill Children.

ABSTRACT: Noninvasive ventilation (NIV) is a common modality employed to treat acute respiratory failure. Most data guiding its use is extrapolated from adult studies. We sought to identify clinical predictors associated with failure of NIV, defined as requiring intubation. This single-center retrospective observational study included children admitted to pediatric intensive care unit (PICU) between July 2014 and June 2016 treated with NIV, excluding postextubation. A total of 148 patients was included. Twenty-seven (18%) failed NIV. There was no difference between the two groups with regard to age, gender, comorbidities, or etiology of acute respiratory failure. Those that failed had higher admission pediatric risk of mortality ( p  = 0.01) and pediatric logistic organ dysfunction ( p

SUBMITTER: Baker AK 

PROVIDER: S-EPMC10411242 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature