Association of prognostic nutritional index with prognostic outcomes in patients with glioma: a meta-analysis and systematic review.

ABSTRACT:

Background

The potential link between Prognostic Nutritional Index (PNI) and prognosis in patients with glioma remains uncertain. This meta-analysis was conducted to assess the clinical value of PNI in glioma patients by integrating all available evidence to enhance statistical power.

Method

A systematic search of databases including Medline, EMBASE, Google Scholar, and Cochrane Library was conducted from inception to January 8, 2023 to retrieve all pertinent peer-reviewed articles. The primary outcome of the study was to examine the association between a high PNI value and overall survival, while secondary outcome included the relationship between a high PNI and progression-free survival.

Results

In this meta-analysis, we included 13 retrospective studies published f

SUBMITTER: Hung KC 

PROVIDER: S-EPMC10411533 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature