Evolution of bone densitometry parameters and risk of fracture in coeliac disease: a 10-year perspective.

ABSTRACT:

Background

Metabolic bone disease is frequently found in patients with coeliac disease (CD). Despite its high prevalence, international guidelines are partially discordant about its management due to the lack of long-term data.

Methods

We retrospectively evaluated a large dataset of prospectively collected data of CD patients assessing the variation of DXA parameters and estimated fracture risk according to the FRAX^® score in a 10-year follow-up. Incident fractures are reported, and the predictive ability of the FRAX^® score is verified.

Results

We identified 107 patients with low bone density (BMD) at the diagnosis of CD and a 10-year follow-up. After improving at the first follow-up, T-scores slowly reduced over time but with no clinically relev

SUBMITTER: Tovoli F 

PROVIDER: S-EPMC10412678 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature