Elevated tissue transglutaminase levels in aqueous humor of congenital cataractous eyes with long axial length.

ABSTRACT:

Objective

To investigate the distribution of axial length (AL) and posterior staphyloma (PS) in congenital cataract (CC) patients. The correlation between AL and the concentration of tissue transglutaminase (TGM2) in the aqueous humor (AH) of cataractous eyes was also evaluated.

Methods

Cross-sectional data were collected from 499 children with CC who underwent phacoemulsification, anterior vitrectomy, and IOL implantation. AL measured by IOLMaster or A-scan ultrasonography and the presence of PS examined by B-scan ultrasonography were recorded. TGM2 levels in AH of 15 CC patients with normal axial length (NAL) and 15 CC patients with PS or long axial length (LAL) were measured by enzyme-linked immunosorbent assay.

Results

The presence of PS in congenital cataractous

SUBMITTER: Yang T 

PROVIDER: S-EPMC10412761 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature