Low serum calcium is a novel predictor of unfavorable prognosis after traumatic brain injury.

ABSTRACT:

Background

Accurate and convenient serological markers for prognosis after traumatic brain injury (TBI) are still lacking. We aimed to explore the predictive value of serum calcium for prognosing outcomes within 6 months after TBI.

Methods

In this multicenter retrospective study, 1255 and 719 patients were included in development and validation cohorts, respectively, and their 6-month prognoses were recorded. Serum calcium was measured through routine blood tests within 24 h of hospital admission. Two multivariate predictive models with or without serum calcium for prognosis were developed. Receiver operating characteristics and calibration curves were applied to estimate their performance.

Results

The patients with lower serum calcium levels had a higher frequency of

SUBMITTER: Li T 

PROVIDER: S-EPMC10412893 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature