Monitoring with circulating tumor cells in the perioperative setting of patients with surgically treated stages I-IIIA NSCLC.

ABSTRACT:

Background

Surgery is regarded as the treatment's cornerstone for early stage and locally advanced non-small cell lung cancer (NSCLC) whenever the tumor is considered resectable. Liquid biopsy is one of the most promising research areas in oncology in the last 10 years, providing a useful non-invasive tool to detect and monitor cancer. The prognostic value of circulating tumor cells (CTCs) has been studied in different cancer types and had been related with a higher risk of relapse and worse prognosis. The aim of this study is to evaluate the prognostic value of CTC detection in patients with stage I-IIIA NSCLC treated with surgery.

Methods

We conducted a prospective, single-center study of 180 consecutive patients with resected and pathological confirmed stage I to IIIA (TN

SUBMITTER: Garitaonaindia Y 

PROVIDER: S-EPMC10413043 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature