Brain metastasis in de novo stage IV breast cancer.

ABSTRACT:

Objectives

Information of brain metastasis (BM) in de novo stage IV breast cancer is lacking, which is an unavoidable problem and dilemma in practice. Understanding the current situation is helpful for the clinical cognition and decision-making.

Methods

We retrospectively analyzed the clinical and survival information of de novo stage IV breast cancer with BM between 2015 and 2019 from the Surveillance, Epidemiology, and End Results (SEER) database. Multivariable logistic and Cox regression analyses were performed to identify predictors of BM and factors associated with all-cause mortality in de novo stage IV breast cancer, respectively. Overall survival (OS) was calculated using Kaplan-Meier and log-rank tests.

Results

Our cohort consisted of 1366 patients with BM in

SUBMITTER: He Y 

PROVIDER: S-EPMC10413138 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature