Long-Term Risk for Mood and Anxiety Disorders After Pediatric Traumatic Brain Injury: A Population-Based, Birth Cohort Analysis.

ABSTRACT:

Objective

To determine whether exposure to traumatic brain injury (TBI) before 10 years of age is associated with development of a mood or anxiety disorder by 25 years of age, and whether sex or injury severity influences this risk.

Setting

Olmsted County, Minnesota.

Participants

A total of 5518 persons born from January 1, 1976, through December 31, 1982.

Design

Population-based, birth cohort study. Children sustaining TBI before 10 years of age (index date) were confirmed by manual record review and classified by injury severity using the Mayo Classification System. Each TBI case was age- and sex-matched to 2 referents from the same birth cohort without a history of TBI at the index date. Cox proportional hazards models were fit to compare the risk of a subse

SUBMITTER: Esterov D 

PROVIDER: S-EPMC10413284 | biostudies-literature | 2023 May-Jun 01

REPOSITORIES: biostudies-literature