Perturbations in gut microbiota composition in patients with polycystic ovary syndrome: a systematic review and meta-analysis.

ABSTRACT:

Background

The results of human observational studies on the correlation between gut microbiota perturbations and polycystic ovary syndrome (PCOS) have been contradictory. This study aimed to perform the first systematic review and meta-analysis to evaluate the specificity of the gut microbiota in PCOS patients compared to healthy women.

Methods

Literature through May 22, 2023, was searched on PubMed, Web of Science, Medline, Embase, Cochrane Library, and Wiley Online Library databases. Unreported data in diversity indices were filled by downloading and processing raw sequencing data. Systematic review inclusion: original studies were eligible if they applied an observational case-control design, performed gut microbiota analysis and reported diversity or abundance measures,

SUBMITTER: Li P 

PROVIDER: S-EPMC10413517 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature