Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application.

ABSTRACT: Continuous glucose monitoring (CGM) allows patients with diabetes to manage critical disease effectively and autonomously and prevent exacerbation. A painless, wireless, compact, and minimally invasive device that can provide CGM is essential for monitoring the health conditions of freely moving patients with diabetes. Here, we propose a glucose-responsive fluorescence-based highly sensitive biodegradable microneedle CGM system. These ultrathin and ultralight microneedle sensor arrays continuously and precisely monitored glucose concentration in the interstitial fluid with minimally invasive, pain-free, wound-free, and skin inflammation-free outcomes at various locations and thicknesses of the skin. Bioresorbability in the body without a need for device removal after use was a key characte

SUBMITTER: Sang M 

PROVIDER: S-EPMC10413647 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature