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ABSTRACT: Objectives
Evidence on the association between frailty and quality of life (QoL) is mostly limited to cross-sectional studies. Thus, the temporal order and potential mechanisms of this association are largely unknown. Our study examines both the directionality of this association and the role of cognition in this association in longitudinal data.Methods
Cross-lagged panel models were employed to examine the temporal relationship between frailty and QoL, as well as cognition's role among 19,649 older adults in Europe. Frailty, QoL, and cognition were assessed using the health deficit index, CASP-12, and 3 standard cognitive tests, respectively.Results
We observed a bidirectional association between frailty and QoL and their dynamics. High initial levels of frailty pr
SUBMITTER: Hu W
PROVIDER: S-EPMC10413812 | biostudies-literature | 2023 May
REPOSITORIES: biostudies-literature