Soil-transmitted helminths: A critical review of the impact of co-infections and implications for control and elimination.

ABSTRACT: Researchers have raised the possibility that soil-transmitted helminth (STH) infections might modify the host's immune response against other systemic infections. STH infections can alter the immune response towards type 2 immunity that could then affect the likelihood and severity of other illnesses. However, the importance of co-infections is not completely understood, and the impact and direction of their effects vary considerably by infection. This review synthesizes evidence regarding the relevance of STH co-infections, the potential mechanisms that explain their effects, and how they might affect control and elimination efforts. According to the literature reviewed, there are both positive and negative effects associated with STH infections on other diseases such as malaria, human im

SUBMITTER: Lebu S 

PROVIDER: S-EPMC10414660 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature