The association between serum adipokines levels with senile osteoporosis: a systematic review and meta-analysis.

ABSTRACT:

Objective

The clinical correlation between adipokines levels in the blood and the incidence of senile osteoporosis (SOP) has not been clearly studied. We conducted this meta-analysis to elucidate the relationship between three common adipokines levels (leptin, adiponectin, and chemerin) and the incidence of SOP.

Methods

We searched databases such as CNKI, CBM, VIP, Wanfang, PubMed, Web of Science, Embase, and the Cochrane Library to collect articles published since the establishment of the database until July 30, 2022.

Results

In total, 11 studies met the selection criteria. Our meta-analysis showed that serum leptin levels were significantly lower (mean difference [MD], -2.53, 95% CI: -3.96 to -1.10, I² = 96%), chemerin levels were significantly hig

SUBMITTER: Wang J 

PROVIDER: S-EPMC10415163 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature