Unexpected high troponin T and I values in a child with hypertrophic cardiomyopathy and acute chest pain: a case report.

ABSTRACT:

Background

Elevated troponin T (cTnT) and/or troponin I (cTnI) can be ascribed to multiple causes, mostly resulting from cardiac tissue damage and in lesser numbers resulting from non-cardiac related causes. The presence of macrotroponins is easily overlooked, with potentially negative consequences.

Case summary

This case report presents a case study of a 12-year-old child known to have MYH7 gene-associated hypertrophic cardiomyopathy with acute chest pain combined with an unexpected high cTnT and cTnI. A cardiac cause was deemed unlikely after additional investigation, as these showed no abnormalities. After consulting a laboratory specialist, it could be concluded that the high cTnT and cTnI were a result of macrotroponin complexes, a protein complex consisting of circulat

SUBMITTER: van Avezaath LK 

PROVIDER: S-EPMC10415857 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature