Prevalence of preconception TORCH infections and its influential factors: evidence from over 2 million women with fertility desire in southern China.

ABSTRACT:

Background

TORCH (Toxoplasma gondii [TOX], Cytomegalovirus [CMV], Rubella virus [RV], and Herpes simplex virus [HSV]) represents pathogens known to traverse the maternal-fetal barrier and cause severe neonatal anomalies. We aimed to assess the prevalence of preconception TOX, CMV, and RV infections among women with fertility desire in southern China, and identify related risk factors.

Methods

Data were obtained from a population-based cross-sectional study conducted as part of the National Free Preconception Health Examination Project. Women planning to conceive within the next 6 months in Guangdong Province were enrolled between 2014 and 2019. Information on sociodemographic, gynecological, and obstetric characteristics was collected. Sera were analyzed for TOX IgG, CMV IgG

SUBMITTER: Han L 

PROVIDER: S-EPMC10416474 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature