Sequence effect on the self-assembly of discrete amphiphilic co-oligomers with fluorene-azobenzene semirigid backbones.

ABSTRACT: Sequences can have a dramatic impact on the unique properties and self-assembly in natural macromolecules, which has received increasing interest. Herein, we report a series of discrete amphiphilic co-oligomers with the same composition but different building blocks in a semirigid backbone. These sequence-defined oligomers possess two primary amine groups on the side chain of the azobenzene building block, and hence, they become amphipathic due to quaternization of the amine groups when protonated in acidic aqueous solution. These oligomer isomers assembled into different nanoparticles, including nanofibers, hollow vesicles and spherical micellar complexes, in a THF/water/HCl mixture under the same conditions. UV-vis absorption spectra, differential scanning calorimetry (DSC) and X-ray sca

SUBMITTER: Ye L 

PROVIDER: S-EPMC10416705 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature