Surveillance, Epidemiology, and End Results database and propensity score matching analysis of postoperative radiotherapy for non-malignant meningioma: A retrospective cohort study.

ABSTRACT:

Background

The clinical effect of postoperative radiotherapy (PORT) in non-malignant meningioma (NMM) has not been well explored.

Methods

A total of 8629 patients with NMM (surgery alone group: n = 7716, postoperative radiotherapy group: n = 913) were obtained from the Surveillance, Epidemiology, and End Results database. Patient profiles were matched by 1:1 propensity score matching (PSM). Logistic regression analysis was performed to identify factors associated with PORT versus surgery alone (SA). Univariate and multivariate Cox regression analyses determined prognostic variables with overall survival (OS) in NMM. Subgroup analyses were performed with Cox proportional hazards regression models.

Results

All the SA (n = 7716) and PORT (n = 913) groups were included. W

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC10417067 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature