Radiological-histopathological discordance in patients transplanted for HCC and its impact on post-transplant outcomes.

ABSTRACT:

Background and aims

Contrast-enhanced cross-sectional imaging is the cornerstone in the diagnosis, staging, and management of HCC, including eligibility for liver transplantation (LT). Radiological-histopathological discordance may lead to improper staging and may impact patient outcomes. We aimed to assess the radiological-histopathological discordance at the time of LT in HCC patients and its impact on the post-LT outcomes.

Methods

We analyzed further the effect of 6-month waiting policy on the discordance. Using United Network for Organ Sharing-Organ Procurement and Transplantation Network (UNOS-OPTN) database, we examined the discordance between pre-LT imaging and explant histopathology for all adult HCC patients who received liver transplants from deceased donors betwee

SUBMITTER: Mohamed IB 

PROVIDER: S-EPMC10417193 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature