Development and validation of a nomogram to predict the recurrence of eyelid sebaceous gland carcinoma.

ABSTRACT:

Purpose

Eyelid sebaceous gland carcinoma (SGC) is a malignancy with fatal risk, high recurrence rate, and pagetoid spread. Thus, recurrence risk prediction and prompt treatment are extremely important. This study aimed to develop a nomogram to predict SGC recurrence based on potential risk factors.

Methods

We conducted a retrospective study to train and test a nomogram based on the clinical data of 391 patients across our hospital (304) and other grass-roots hospitals (87). After Cox regression, predictors included in the nomogram were selected, and sensitivity, specificity, concordance index (C-index), etc., were calculated to test their discrimination ability.

Results

After a median follow-up period of 4.12 years, SGC recurred in 52 (17.11%) patients. The 1-, 2-, an

SUBMITTER: Nie Z 

PROVIDER: S-EPMC10417194 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature