Incidence and Predictors for Oncologic Etiologies in Chinese Children with Pituitary Stalk Thickening.

ABSTRACT:

Background

With the increasing use of magnetic resonance imaging (MRI) in the evaluation of children with endocrine disorders, pituitary stalk thickening (PST) poses a clinical conundrum due to the potential for underlying neoplasms and challenges in obtaining a tissue biopsy. The existing literature suggests Langerhans cell histiocytosis (LCH) to be the commonest (16%) oncologic cause for PST, followed by germ cell tumors (GCTs, 13%) (CCLG 2021). As the cancer epidemiology varies according to ethnicity, we present herein the incidence and predictors for oncologic etiologies in Hong Kong Chinese children with PST.

Methods

Based on a territory-wide electronic database, we reviewed patients aged < 19 years who presented to three referral centers with endocrinopathies between 2

SUBMITTER: Li MWT 

PROVIDER: S-EPMC10417368 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature