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Beyond Macromolecules: Extracellular Vesicles as Regulators of Inflammatory Diseases.


ABSTRACT: Inflammation is the defense mechanism of the immune system against harmful stimuli such as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by tissue redness, swelling, heat generation, pain, and loss of tissue functions. Inflammation is essential in the recruitment of immune cells at the site of infection, which not only aids in the elimination of the cause, but also initiates the healing process. However, prolonged inflammation often brings about several chronic inflammatory disorders; hence, a balance between the pro- and anti-inflammatory responses is essential in order to eliminate the cause while producing the least damage to the host. A growing body of evidence indicates that extracellular vesicles (EVs) play a major role in cell-cell communication vi

SUBMITTER: Das K 

PROVIDER: S-EPMC10417494 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature