Grey Matter Reshaping of Language-Related Regions Depends on Tumor Lateralization.

ABSTRACT: A brain tumor in the left hemisphere can decrease language laterality as assessed through fMRI. However, it remains unclear whether or not this decreased language laterality is associated with a structural reshaping of the grey matter, particularly within the language network. Here, we examine if the disruption of the language hubs exclusively affects the macrostructural properties of the contralateral homologues or whether it affects both hemispheres. This study uses voxel-based morphometry applied to high-resolution MR T1-weighted MPRAGE images from 31 adult patients' left hemisphere, which is dominant for language. Eighteen patients had brain tumors in the left hemisphere, and thirteen had tumors in the right hemisphere. A cohort of 71 healthy individuals matched with respect to age and

SUBMITTER: Manso-Ortega L 

PROVIDER: S-EPMC10417790 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature