Dynamics of Podospora anserina Genome Evolution in a Long-Term Experiment.

ABSTRACT: The Podospora anserina long-term evolution experiment (PaLTEE) is the only running filamentous fungus study, which is still going on. The aim of our work is to trace the evolutionary dynamics of the accumulation of mutations in the genomes of eight haploid populations of P. anserina. The results of the genome-wide analysis of all of the lineages, performed 8 years after the start of the PaLTEE, are presented. Data analysis detected 312 single nucleotide polymorphisms (SNPs) and 39 short insertion-deletion mutations (indels) in total. There was a clear trend towards a linear increase in the number of SNPs depending on the experiment duration. Among 312 SNPs, 153 were fixed in the coding regions of P. anserina genome. Relatively few synonymous mutations were found, exact

SUBMITTER: Kudryavtseva OA 

PROVIDER: S-EPMC10418817 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature