Evolution of Vaccines Formulation to Tackle the Challenge of Anti-Microbial Resistant Pathogens.

ABSTRACT: The increasing diffusion of antimicrobial resistance (AMR) across more and more bacterial species emphasizes the urgency of identifying innovative treatment strategies to counter its diffusion. Pathogen infection prevention is among the most effective strategies to prevent the spread of both disease and AMR. Since their discovery, vaccines have been the strongest prophylactic weapon against infectious diseases, with a multitude of different antigen types and formulative strategies developed over more than a century to protect populations from different pathogens. In this review, we review the main characteristics of vaccine formulations in use and under development against AMR pathogens, focusing on the importance of administering multiple antigens where possible, and the challenges associ

SUBMITTER: Tognetti F 

PROVIDER: S-EPMC10418901 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature