Local tumor destruction and liver resection increase overall survival in intermediate/advanced hepatocellular carcinoma patients: evidence from a population-based study.

ABSTRACT:

Background

Liver resection (LR) and local tumor destruction (LTD) are effective treatments, but not commonly recommended for patients with intermediate/advanced hepatocellular carcinoma (HCC). This study aimed to explore whether LR/LTD could improve overall survival (OS) of these patients, and to identify the patients who will most likely benefit from LR/LTD.

Methods

Data of patients with intermediate/advanced HCC between 2001 and 2018 were extracted from Surveillance, Epidemiology, and End Results database. OS was compared between HCC patients who received LR/LTD and those who did not. A nomogram was constructed for predicting OS, and it was then validated.

Results

A total of 535 eligible patients were included, among which 128 received LR/LTD while 407 did not. Sign

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC10419194 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature