Genomic and Transcriptomic Research in the Discovery and Application of Colorectal Cancer Circulating Markers.

ABSTRACT: Colorectal cancer (CRC) is the most frequently occurring malignancy in the world. However, the mortality from CRC can be reduced through early diagnostics, selection of the most effective treatment, observation of the therapy success, and the earliest possible diagnosis of recurrences. A comprehensive analysis of genetic and epigenetic factors contributing to the CRC development is needed to refine diagnostic, therapeutic, and preventive strategies and to ensure appropriate decision making in managing specific CRC cases. The liquid biopsy approach utilizing circulating markers has demonstrated its good performance as a tool to detect the changes in the molecular pathways associated with various cancers. In this review, we attempted to brief the main tendencies in the development of circula

SUBMITTER: Ponomaryova AA 

PROVIDER: S-EPMC10419249 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature