Co-Existence of bla_NDM-1, bla_OXA-23, bla_OXA-64, bla_PER-7 and bla_ADC-57 in a Clinical Isolate of Acinetobacter baumannii from Alexandria, Egypt.

ABSTRACT: The increasing rates of antimicrobial resistance among carbapenem-resistant Acinetobacter baumannii in the Middle East and North Africa are one of the major concerns for healthcare settings. We characterised the first A. baumannii isolate harbouring five β-lactamases identified in Egypt. The isolate Ale25 was obtained from an ICU patient of a hospital from Alexandria. The isolate was phenotypically and genotypically screened for carbapenemase genes. The isolate was resistant to carbapenems, aminoglycosides, fluoroquinolones and cefiderocol. Whole-Genome Sequencing identified five β-lactamase genes, bla_NDM-1, bla_OXA-23, bla_OXA-64, bla_PER-7 and bla_ADC-57, together with other antibiotic res

SUBMITTER: Sanchez-Urtaza S 

PROVIDER: S-EPMC10419532 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature