Ontology highlight
ABSTRACT:
SUBMITTER: Nurmi V
PROVIDER: S-EPMC10420400 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Nurmi Visa V Knight Chanice C Estcourt Lise L Hepojoki Jussi J Lamikanra Abigail A AA Tsang Hoi P HP Roberts David J DJ Polack Fernando P FP Simmonds Peter P Hedman Klaus K Alvarez-Paggi Damian D Harvala Heli H
The Journal of infectious diseases 20230801 3
Convalescent plasma (CP) treatment of coronavirus disease 2019 (COVID-19) has shown significant therapeutic effect when administered early (eg, Argentinian trial showing reduced hospitalization) but has in general been ineffective (eg, REMAP-CAP trial without improvement during hospitalization). To investigate whether the differences in CP used could explain the different outcomes, we compared neutralizing antibodies, anti-spike IgG, and avidity of CP used in the REMAP-CAP and Argentinian trials ...[more]