Vitamin E and Multiple Health Outcomes: An Umbrella Review of Meta-Analyses.

ABSTRACT: The relationship between vitamin E intake or circulating α-tocopherol and various health outcomes is still debatable and uncertain. We conducted an umbrella review to identify the relationships between vitamin E intake or circulating tocopherol and health outcomes by merging and recalculating earlier meta-analyses. The connections that were found to be statistically significant were then classified into different evidence levels based on p values, between-study heterogeneity, prediction intervals, and small study effects. We finally included 32 eligible meta-analyses with four vitamin E sources and 64 unique health outcomes. Only the association between circulating α-tocopherol and wheeze or asthma in children was substantiated by consistent evidence. Suggestive evidence was suggest

SUBMITTER: Xiong Z 

PROVIDER: S-EPMC10421296 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature