Fracture risk among patients with cancer compared to individuals without cancer: a population-based study.

ABSTRACT:

Background

Patients with cancer may be at increased risk of osteoporosis and fracture; however, gaps exist in the existing literature and the association between cancer and fracture requires further examination.

Methods

We conducted a population-based cohort study of Ontario patients with cancer (breast, prostate, lung, gastrointestinal, haematologic) diagnosed between January 2007 to December 2018 and 1:1 matched non-cancer controls. The primary outcome was incident fracture (end of follow-up December 2019). Multivariable Cox regression analysis was used to estimate the relative fracture risk with sensitivity analysis accounting for competing risk of death.

Results

Among 172,963 cancer patients with non-cancer controls, 70.6% of patients with cancer were <65 years ol

SUBMITTER: Gong IY 

PROVIDER: S-EPMC10421906 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature