Comparative analysis of effectiveness for phage cocktail development against multiple Salmonella serovars and its biofilm control activity.

ABSTRACT: Foodborne diseases are a major challenge in the global food industry, especially those caused by multidrug-resistant (MDR) bacteria. Bacteria capable of biofilm formation, in addition to MDR strains, reduce the treatment efficacy, posing a significant threat to bacterial control. Bacteriophages, which are viruses that infect and kill bacteria, are considered a promising alternative in combating MDR bacteria, both in human medicine and animal production. Phage cocktails, comprising multiple phages, are commonly employed to broaden the host range and prevent or delay the development of phage resistance. There are numerous techniques and protocols available to evaluate the lytic activity of bacteriophages, with the most commonly used methods being Spot Test Assays, Efficiency of Plating (EOP)

SUBMITTER: Ribeiro JM 

PROVIDER: S-EPMC10421930 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature