Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar.

ABSTRACT:

Background

Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD).

Objective

The study aimed to investigate the association between selected single nucleotide polymorphisms (SNPs) with dyslipidemia and increased susceptibility risks of CVD, NAFLD, and/or T2DM in dyslipidemia patients in comparison with healthy control individuals from the Qatar genome project.

Methods

A community-based cross-sectional study was conducted among 2933 adults (859 dyslipidemia patients and 2074 healthy control individuals) from April to December 2021 to investigate the association between 331 selected SNPs with dyslipidemia and increased susceptibility risks of CVD, NAFLD and/o

SUBMITTER: Al-Sharshani D 

PROVIDER: S-EPMC10422074 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature