Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys.

ABSTRACT:

Objectives

To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin-1 (ISM1) and obesity-related phenotypes in a population of Spanish children and to investigate the plausible molecular alterations behind the alteration of the serum levels of this protein in children with obesity.

Methods

The study population is a sub-cohort of the PUBMEP research project, consisting of a cross-sectional population of 119 pubertal children with overweight (17 boys, 19 girls), obesity (20 boys, 25 girls), and normal weight (17 boys, 21 girls). All subjects were classified into experimental groups according to their sex, obesity, and insulin resistance (IR) status. They were counted anthropometry, glucose and lipid metabolism, inflammati

SUBMITTER: Ruiz-Ojeda FJ 

PROVIDER: S-EPMC10423122 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature