Differential diagnosis of adrenal adenomas and metastases using spectral parameters in dual-layer detector spectral CT.

ABSTRACT:

Objective

To assess the diagnostic value of spectral parameters in differentiating adrenal adenomas from metastases based on dual-layer detector spectral CT (DLSCT).

Materials and methods

Patients with adenomas or metastases who underwent enhanced DLSCT of the adrenals were enrolled. The CT values of virtual non-contrast images (CT_VNC), iodine density (ID) values, and Z-effective (Z-eff) values, the normalized iodine density (NID) values, slopes of spectral HU curves (s-SHC), and iodine-to-CT_VNC ratios of the tumors were measured in each phase. Receiver operating characteristic (ROC) curves were used to compare the diagnostic values.

Results

Ninety-nine patients with 106 adrenal lesions (63 adenomas, 43 metastases) were included. In the venous ph

SUBMITTER: Wu LD 

PROVIDER: S-EPMC10423139 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature