Feasibility of in vivo magnetic resonance elastography of mesenteric adipose tissue in Crohn's disease.

ABSTRACT:

Background

Although there is growing evidence that functional involvement and structural changes of mesenteric adipose tissue (MAT) influence the course of Crohn's disease (CD), its viscoelastic properties remain elusive. Therefore, we aimed to investigate the viscoelastic properties of MAT in CD using magnetic resonance elastography (MRE), providing reference values for CD diagnosis.

Methods

In this prospective proof-of-concept study, 31 subjects (CD: n=11; healthy controls: n=20) were consecutively enrolled in a specialized care center for inflammatory bowel diseases (tertiary/quaternary care). Inclusion criteria for the CD patients were a clinically and endoscopically established diagnosis of CD based on the clinical record, absence of other concurrent bowel diseases, sch

SUBMITTER: Jensen LJ 

PROVIDER: S-EPMC10423387 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature