A preliminary study on the effect of renal function on the metabolism of ¹⁸F-FDG in the human cerebellum.

ABSTRACT:

Background

The cerebellum is less affected by normal aging or neurodegenerative diseases, the aim of this paper is to investigate the effect of renal function status on uptake of 2-deoxy-2-[¹⁸F]fluoro-D-glucose (¹⁸F-FDG) in human cerebellum based on independent creatinine (CRE) or blood urea nitrogen (BUN) levels.

Methods

A total of 253 patients who underwent ¹⁸F-FDG PET/CT scans were included. The patients were divided into groups according to renal function status: 201 patients with normal renal function, 16 patients with increase CRE, 36 patients with decrease CRE, and 31 patients with abnormal BUN. The maximum standardized uptake values were obtained in regions of interest (ROIs) for multiple tissue types (right cerebellum, right lobe of

SUBMITTER: Rachid A 

PROVIDER: S-EPMC10423388 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature