Pneumococcal colonization and severity of pneumonia in hospitalized Cambodian children following introduction of the 13-valent pneumococcal conjugate vaccine.

ABSTRACT:

Objectives

This study sought to characterize pneumococcal colonization and clinical/radiological features in Cambodian children admitted to hospital with an illness compatible with pneumonia following national introduction of the 13-valent pneumococcal conjugate vaccine (PCV13).

Methods

Children aged 0-59 months admitted to Angkor Hospital for Children who met the World Health Organization (WHO) case definition for clinical pneumonia were enrolled over a 3-year period. Clinical, radiological and vaccination data were collected at enrolment. A nasopharyngeal swab was collected for detection of pneumococcal colonization using the WHO standard culture method.

Results

Between 1 September 2015 and 31August 2018, 2209 analysable illness episodes were enrolled. Pneumococci w

SUBMITTER: Miliya T 

PROVIDER: S-EPMC10423667 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature