Effects and safety of hypertonic saline combined with airway clearance in non-hospitalized children with recurrent wheezing.

ABSTRACT:

Background

The International Study of Wheezing in Infants defines recurrent wheezing as the presence of three or more medically documented episodes of wheezing within one year. To date, there is no evidence on the use of hypertonic saline (HS) combined with airway clearance techniques (ACT) for children with recurrent wheezing treated in an outpatient setting. Therefore, this is the first study to explore the use of such interventions in infants with recurrent wheezing.

Objectives

To evaluate the effects and safety of a three-month protocol including HS and ACT for non-hospitalized infants with recurrent wheezing.

Methods

Randomized, double-blind, controlled trial, including outpatient infants with recurrent wheezing. Children were randomized to either 3% HS or 0.9% s

SUBMITTER: Gonzalez-Bellido V 

PROVIDER: S-EPMC10423675 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature