Studying additive effects of combining rTMS with cognitive control training: a pilot investigation.

ABSTRACT:

Background

Repetitive transcranial magnetic stimulation (rTMS) on the dorsolateral prefrontal cortex (DLPFC) is an effective treatment for depression that has been proposed to work via the enhancement of cognitive control. Cognitive control training (CCT) can also alleviate depression by relying on DLPFC activation. As the additive effects of rTMS and CCT are unclear, we set out to conduct a within-subject pilot study in healthy controls.

Methods

Seventeen participants received two sessions of individualized resting-state connectivity-guided high-frequency rTMS, while randomly performing CCT or a control task. After each session, a negative mood was induced.

Results

We found effects on mood and cognitive control after rTMS + CCT as well as rTMS + control, which were i

SUBMITTER: Dalhuisen I 

PROVIDER: S-EPMC10423931 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature