Did the early full genome sequencing of yeast boost gene function discovery?

ABSTRACT:

Background

Although the genome of Saccharomyces cerevisiae (S. cerevisiae) was the first one of a eukaryote organism that was fully sequenced (in 1996), a complete understanding of the potential of encoded biomolecular mechanisms has not yet been achieved. Here, we wish to quantify how far the goal of a full list of S. cerevisiae gene functions still is.

Results

The scientific literature about S. cerevisiae protein-coding genes has been mapped onto the yeast genome via the mentioning of names for genomic regions in scientific publications. The match was quantified with the ratio of a given gene name's occurrences to those of any gene names in the article. We find that ~ 230 elite genes with ≥ 75 full publication equivalents (FPEs, FPE = 1 is an idealized publication referrin

SUBMITTER: Tantoso E 

PROVIDER: S-EPMC10424406 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature