Feasibility of the pupillary pain index as a guide for depth of analgesia during opioid-sparing anesthesia with continuous infusion of dexmedetomidine.

ABSTRACT:

Background

The pupillary dilation reflex (PDR) is an objective indicator of analgesic levels in anesthetized patients. Through measurement of the PDR during increasing tetanic stimulation (10-60 mA), it is possible to obtain the pupillary pain index (PPI), a score that assesses the level of analgesia.

Objectives

The depth of analgesia during opioid-sparing anesthesia (OSA) with continuous infusion of dexmedetomidine in addition to general anesthesia was assessed.

Design

Observational prospective feasibility pilot study SETTING: This study was performed in the operating rooms of the Spedali Civili University-affiliated hospital of Brescia, Italy.

Patients

Forty-five adults who underwent elective open (5-cm incision) surgery under general anesthesia (78% inhalati

SUBMITTER: Stefanini M 

PROVIDER: S-EPMC10424415 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature