Nomogram to predict unfavorable outcome of endovascular thrombectomy for large ischemic core.

ABSTRACT:

Objective

The prognosis for patients presenting with a large ischemic core (LIC) following endovascular thrombectomy is relatively poor. This study aimed to construct and validate a nomogram for predicting 3-month unfavorable outcome in patients with anterior circulation occlusion-related LIC who underwent endovascular thrombectomy.

Methods

A retrospective training cohort and a prospective validation cohort of patients with a large ischemic core were studied. The diffusion weighted imaging related radiomic features and pre-thrombectomy clinical features were collected. After the selection of relevant features, a nomogram predicting modified Rankin Scale score of 3-6 as an unfavorable outcome was established. The discriminatory value of the nomogram was evaluated with a recei

SUBMITTER: Han N 

PROVIDER: S-EPMC10424651 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature