Ggpicrust2: an R package for PICRUSt2 predicted functional profile analysis and visualization.

ABSTRACT:

Summary

Microbiome research is now moving beyond the compositional analysis of microbial taxa in a sample. Increasing evidence from large human microbiome studies suggests that functional consequences of changes in the intestinal microbiome may provide more power for studying their impact on inflammation and immune responses. Although 16S rRNA analysis is one of the most popular and a cost-effective method to profile the microbial compositions, marker-gene sequencing cannot provide direct information about the functional genes that are present in the genomes of community members. Bioinformatic tools have been developed to predict microbiome function with 16S rRNA gene data. Among them, PICRUSt2 (Phylogenetic Investigation of Communities by Reconstruction of Unobserved States) has b

SUBMITTER: Yang C 

PROVIDER: S-EPMC10425198 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature