Procalcitonin and C-reactive protein to rule out early bacterial coinfection in COVID-19 critically ill patients.

ABSTRACT:

Purpose

Although the prevalence of community-acquired respiratory bacterial coinfection upon hospital admission in patients with coronavirus disease 2019 (COVID-19) has been reported to be < 5%, almost three-quarters of patients received antibiotics. We aim to investigate whether procalcitonin (PCT) or C-reactive protein (CRP) upon admission could be helpful biomarkers to identify bacterial coinfection among patients with COVID-19 pneumonia.

Methods

We carried out a multicentre, observational cohort study including consecutive COVID-19 patients admitted to 55 Spanish intensive care units (ICUs). The primary outcome was to explore whether PCT or CRP serum levels upon hospital admission could predict bacterial coinfection among patients with COVID-19 pneumonia. The secondary o

SUBMITTER: Galli F 

PROVIDER: S-EPMC10425511 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature