The Association between Infant Birth Weight, Head Circumference, and Neurodevelopmental Outcomes.

ABSTRACT:

Objective

The aim of this study was to evaluate whether being small for gestational age (SGA) or large for gestational age (LGA) or having a small or large head circumference (HC) at birth is associated with adverse neurodevelopmental outcomes.

Study design

This is a secondary analysis of a multicenter negative randomized trial of thyroxine therapy for subclinical hypothyroid disorders in pregnancy. The primary outcome was child intelligence quotient (IQ) at 5 years of age. Secondary outcomes included several neurodevelopmental measures. Associations between the outcomes in children with SGA (<10th percentile) or LGA (>90th percentile) birth weights, using ethnicity- and sex-specific population nomogram as well as nomograms from the National Fetal Growth (NFG) study, were co

SUBMITTER: Costantine MM 

PROVIDER: S-EPMC10425571 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature