Time to Publication and Time-Lag Publication Bias for Randomized Trials on Connective Tissue Diseases.

ABSTRACT:

Objective

To assess the time from completion to publication of randomized controlled trials (RCTs) on connective tissue diseases (CTDs), investigate the factors associated with, and explore the influence of significance of study results on time to publication (time-lag publication bias).

Methods

We included interventional, phase 2/3, 3, or 4 RCTs on CTDs registered in Clinicaltrials.gov from 2000 to 2016, whose results had been published in a peer-review journal less than 5 years after their completion. Main trial features, including the significance of primary outcome results, were collected. Time to publication was the time from study completion to the earliest publication date. Multivariable linear regression was used to identify factors associated with time to publicatio

SUBMITTER: Mongin D 

PROVIDER: S-EPMC10425588 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature