Current clinical practices and challenges in molecular testing: a GOAL Consortium Hematopathology Working Group report.

ABSTRACT: While molecular testing of hematologic malignancies is now standard of care, there is variability in practice and testing capabilities between different academic laboratories, with common questions arising on how to best meet clinical expectations. A survey was sent to hematopathology subgroup members of the Genomics Organization for Academic Laboratories consortium to assess current and future practice and potentially establish a reference for peer institutions. Responses were received from 18 academic tertiary-care laboratories regarding next-generation sequencing (NGS) panel design, sequencing protocols and metrics, assay characteristics, laboratory operations, case reimbursement, and development plans. Differences in NGS panel size, use, and gene content were reported. Gene content for

SUBMITTER: Lee TD 

PROVIDER: S-EPMC10425685 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature